Exploring the relationship between natural killer cells and cutaneous squamous cell carcinoma development
نویسندگان
چکیده
cSCC: cutaneous squamous cell carcinoma FNKD: functional natural killer cell deficiency HPV: human papillomavirus KIR: killer cell immunoglobulin-like receptor MHC: major histocompatibility complex NK: natural killer INTRODUCTION There are many conditions associated with the formation of numerous cutaneous squamous cell carcinomas (cSCCs), including, among others, xeroderma pigmentosum, epidermolysis bullosa, epidermodysplasia verruciformis, Ferguson-Smith syndrome, Grzybowski syndrome, and Bloom syndrome. We report the first case of multiple cSCCs developing in the setting of functional natural killer cell deficiency (FNKD). This case reveals a potential underlying relationship between natural killer (NK) cells and cSCC development.
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